TALLAHASSEE, FL - OCTOBER 01: Florida State Seminoles head coach Jimbo Fisher before the game against the North Carolina Tar Heels at Doak Campbell Stadium on October 1, 2016 in Tallahassee, Florida. (Photo by Jeff Gammons/Getty Images)

FSU dealt another tough blow ahead of their biggest game of the year

This is arguably their biggest game of the season.

The Florida State Seminoles will have to go into their tilt against Clemson already down a member on defense, missing safety Derwin James, and now they'll be hit on offense as well, with wideout Bobo Wilson officially ruled out with a foot injury.

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"You're talking about a guy who's played a lot of games, played a lot of ball, done a lot of things, and played in a lot of big-time environments and atmospheres," Fisher said of Wilson in quotes distributed by the team, per College Football Talk. "That all sounds good on paper.

"Now, do I think [these younger receivers] can go out there and play? Yes. Do I think they can be really good players? Yes. Have they practiced well? Yes. [Tate] has done more in games so far, but they have a chance to be really good players. I'm hoping they go out there and play."

With Wilson out, the 'Noles will have to rely on a combination of Auden Tate, Nyqwan Murray and Da'Vante Phillips.

The 5'10" senior has 30 receptions on the season for 390 yards and one touchdown. He's also an electric return man, taking back nine punts for 155 yards and a score.