The NFL is celebrating schedule release week by providing a drip of information. The league has revealed two more primetime matchups.
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The NFL has set the first Thursday Night Football matchup of the season and the first Monday Night Football matchup. This follows the announcement that the New York Giants will host the Dallas Cowboys in the the first Sunday Night Football game of the 2026 season.
The first Thursday Night Football primetime game will kick off Week 2 of the NFL season. The Buffalo Bills will host the Detroit Lions as they showcase their brand new stadium. This game will air on Prime Video at 8:15 p.m. ET on Sept. 17.
Buffalo will host the Lions at the Bills new stadium on Thursday Night Football in week two. pic.twitter.com/3lRtpjhhT0
— Adam Schefter (@AdamSchefter) May 11, 2026
According to information provided by the NFL, this Thursday Night Football game will serve as the stadium's debut. That means that the Bills will kick off the season on the road before returning home for Week 2.
The first Monday Night Football game will close out the NFL's opening week. The Denver Broncos and Kansas City Chiefs will continue their rivalry in primetime. This game will air at 8:20 p.m. ET on Sept. 14. ABC, ESPN, ESPN2, and ESPN Deportes will provide coverage.
The NFL did not reveal the location of this game. This remains to be determined as the league continues to finalize the full schedule ahead of Thursday's big reveal.
The matchup between the Broncos and the Chiefs will feature some major question marks, both involving the quarterbacks. Broncos QB Bo Nix sustained a broken ankle in a divisional round game against the Bills. He should be ready to return to the lineup by the regular season.
Chiefs QB Patrick Mahomes missed the final three weeks of the 2025 season after tearing his ACL and LCL. He could be back in the lineup for this opening game, or he could still be recovering. His health remains the biggest question heading toward the season.
The full schedule reveal will take place on Thursday, May 14, at 8 p.m. ET. NFL.com and NFL+ will provide coverage as the league reveals when and where every regular-season matchup will happen.
